Enzyme function is central to student understanding of multiple topics within the biochemistry curriculum. In particular, students must understand how enzymes and substrates interact with one another. This manuscript describes the development of a 15-item Enzyme–Substrate Interactions Concept Inventory(ESICI) that measures student understanding of enzyme–substrate interactions. The validity and reliability of ESICI data were established through multiple methods. Results from the administration of the ESICI to biochemistry students across the United States (N = 707) are discussed in terms of instrument quality. The manuscript concludes with suggestions for how to use the ESICI for both teaching and biochemistry education research.

Each DR K-12 project has formative and summative evaluation, which are different from the project’s own R&D activities and instead should support and measure the effectiveness of those activities. This paper discusses evaluation options for investigators and evaluators to consider. Read the full paper for a description of these options.

To foster knowledge use among policy makers or practitioners requires a substantial effort that invests in sustained interaction and enlists a range of supports for the prospective knowledge users. This paper discusses some options for more effective dissemination efforts that could lead to knowledge use. Read the full paper for a description of these options.